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Someril 5Mg 30 Tablets Melatonin, often referred to as the �sleep hormone,� is naturally produced by the body when it gets dark and plays a key role in regulating the sleep-wake cycle. It is synthesized from the amino acid tryptophan and the neurotransmitter serotonin. Disruptions to your daily rhythm such as night shifts, jet lag, low daylight exposure, stress, or lack of physical activity can interfere with melatonin production. This can lead to symptoms like difficulty falling asleep, frequent nighttime awakenings, and restless, poor-quality sleep. Supplements that support melatonin production can help restore balance and promote restful sleep.